What are the External Models of Pharma R&D?

What are some fundamental problems that pharmaceutical companies are facing and how are they solving them? The authors (Merck, Sanofi, and The Boston Consulting Group) cite decreased Research and Development (R&D) productivity and rising customer expectations as challenges to pharma.

What are the External Models of Pharma R&D?

What are some fundamental problems that pharmaceutical companies are facing and how are they solving them? The authors (Merck, Sanofi, and The Boston Consulting Group) cite decreased Research and Development (R&D) productivity and rising customer expectations as challenges to pharma.

Why did Merck Develop a Screening Paradigm for Combination Therapies?

Sometimes two drugs are better than one. Combinations of therapies can be more effective than just one in isolation, thus a lower doses of each can be administered. The authors cite and test in this paper antiinfectives and cancer chemotherapeutics

Why did Merck Develop a Screening Paradigm for Combination Therapies?

Sometimes two drugs are better than one. Combinations of therapies can be more effective than just one in isolation, thus a lower doses of each can be administered. The authors cite and test in this paper antiinfectives and cancer chemotherapeutics

How can Drugs be Made Available to the Developing World?

John Kay of the London School of Economics wrote a piece in the Financial Times (UK) in March 2015 entitled “The True Value of a Life is Not About the Pharmaceutical costs” advocating for a national license tax to make

How can Drugs be Made Available to the Developing World?

John Kay of the London School of Economics wrote a piece in the Financial Times (UK) in March 2015 entitled “The True Value of a Life is Not About the Pharmaceutical costs” advocating for a national license tax to make

Is There a Decline in Financial Returns From New Drugs?

Industry observers predicted that the profitability of the pharmaceutical industry would decline as a result of the expiration of patents of blockbuster drug. Blockbuster drugs generate $1 billion in revenue a year and include Lipitor (Pfizer) at $12.5 billion/year, Plavix

Is There a Decline in Financial Returns From New Drugs?

Industry observers predicted that the profitability of the pharmaceutical industry would decline as a result of the expiration of patents of blockbuster drug. Blockbuster drugs generate $1 billion in revenue a year and include Lipitor (Pfizer) at $12.5 billion/year, Plavix

Why is Pfizer interested in TPBG Gene Replacement?

What is TPBG? Trophoblast glycoprotein (TPBG) is an oncofetal integral plasma membrane protein found in higher levels in embryonic development than healthy adults. The extracellular domain assists in cell adhesion and epithelial-mesenchymal transition, both occuring in early development and tumor

Why is Pfizer interested in TPBG Gene Replacement?

What is TPBG? Trophoblast glycoprotein (TPBG) is an oncofetal integral plasma membrane protein found in higher levels in embryonic development than healthy adults. The extracellular domain assists in cell adhesion and epithelial-mesenchymal transition, both occuring in early development and tumor

How is Crowdsourcing being used in Pharma?

Crowdsourcing is a method of soliciting, obtaining or collaborating on projects or procuring goods through a large community rather than by traditional suppliers. Why would Pharma utilize Crowdsourcing? Using crowdsourcing for pharmaceutical endeavors seems obvious, as the venture is high-risk. 

How is Crowdsourcing being used in Pharma?

Crowdsourcing is a method of soliciting, obtaining or collaborating on projects or procuring goods through a large community rather than by traditional suppliers. Why would Pharma utilize Crowdsourcing? Using crowdsourcing for pharmaceutical endeavors seems obvious, as the venture is high-risk. 

Can polymer gels be used to deliver drugs?

Biosyntech of Canada released results in December 2000 about its injectable hydrogel for the delivery of therapeutics. The company claims this hydrogel can deliver small molecules, peptides, and macromolecules like recombinant proteins. They had positive results that there was no

Can polymer gels be used to deliver drugs?

Biosyntech of Canada released results in December 2000 about its injectable hydrogel for the delivery of therapeutics. The company claims this hydrogel can deliver small molecules, peptides, and macromolecules like recombinant proteins. They had positive results that there was no